Polymerized liposomes as stable oxygen-carriers

Liposomes as drug carriers.

Liposomes are artificially prepared vesicles made of lipid bilayer. Liposomes can be filled with drugs, and used to deliver drugs for cancer and other diseases. Amongst the various carrier, few drug carrier reached the stages of clinical trails where phospholipid vesicles (liposome) show strong potential for effective drug delivery to the site of action. Liposomes can be composed of naturally-d...

Liposomes as carriers in vivo for methotrexate.

In differential activation, advantage is taken of the different sensitivity of the various organelles towards digitonin which is added in uitro to liver homogenates (HuybrechtsGodin & Jacques, 1974). The method can be applied to the localization of exogenous material without parallel treatment by ancillary lysosomotropic compounds. Table 2 illustrates the digitonin-induced release of latent mar...

Liposomes as Carriers of Anticancer Drugs

Liposomes as carriers for DNA-PNA hybrids.

Peptide nucleic acids (PNAs) are DNA mimics composed of N-(2-aminoethyl)glycine units. This structure gives to PNAs (a) resistance to DNases and proteinases, (b) capacity to hybridize with high affinity to complementary sequences of single-stranded RNA and DNA, and (c) capacity to form highly stable (PNA)(2)-RNA triplexes with RNA targets. Furthermore, DNA-PNA hybrid molecules are capable to re...

Availability of liposomes as drug carriers to the brain.

Phospholipid vesicles, also known as liposomes, were examined for their ability to act as a drug carrier to the brain. 9-Amino-1,2,3,4-tetrahydroacridine (THA), a centrally acting acetylcholinesterase inhibitor, was used as a model drug. THA was encapsulated in dehydration-rehydration vesicles (DRV) composed of egg yolk phosphatidylcholine, cholesterol and dipalmitoyl-phosphatidic acid (molar r...